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34885-M

Sigma-Aldrich

Methanol

≥99.9%, gradient grade, suitable for HPLC

Synonym(s):

Methyl alcohol

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About This Item

Linear Formula:
CH3OH
CAS Number:
67-56-1
Molecular Weight:
32.04
Beilstein:
1098229
EC Number:
200-659-6
MDL number:
MFCD00004595
UNSPSC Code:
15101803
PubChem Substance ID:
329755085
NACRES:
NA.05
grade:
gradient grade
Assay:
≥99.9%
technique(s):
HPLC: suitable
bp:
64.7 °C (lit.)
vapor pressure:
410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)
Pricing and availability is not currently available.

Product Name

Methanol, suitable for HPLC, gradient grade, ≥99.9%

grade

gradient grade

vapor density

1.11 (vs air)

vapor pressure

410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

725 °F

expl. lim.

36 %

technique(s)

HPLC: suitable

impurities

KMnO4 red. matter (as O), in accordance
≤0.0005% free alkali (as NH3)
≤0.0005% non-volatile matter
≤0.001% acetaldehyde
≤0.001% acetone (GC)
≤0.001% formaldehyde
≤0.02% water (Karl Fischer)
≤1 ppb fluorescence (quinine) at 254 nm
≤1 ppb fluorescence (quinine) at 365nm

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General description

Thermochemical conversion of methanol to C2-C10 hydrocarbons in the presence of shape-selective zeolites has been reported.[1] Its oxidation on Ru-Pt catalyst system by ruthenium ad-atoms has been proposed.[2]

Application

Methanol (MeOH) has been used as an eluent in the HPLC estimation of malondialdehyde in plasma, which is an indicator of oxidative stress.[3]
It may be used in the following studies:
  • Colony forming unit-fibroblast assay of bone marrow mononuclear cells.[4]
  • As solvent for the preparation of extracts of hyphae of Aspergillus for the estimation of gliotoxin by reversed phase-HPLC.[5]
  • Immunofluorescence studies.[6]
  • To compose eluent for the ion-pair reverse-phase HPLC isolation of nucleotides and their decomposition products.[7]

Packaging

View returnable container options.

Preparation Note

Product filtered through a 0.2 μm filter

Other Notes

Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.
Important notice
  • The article number 34885-6X1L-M will be discontinued. Please order the single bottle 34885-1L-M which is physically identical with the same exact specifications.

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Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

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    Certificates of Analysis (COA)

    Lot/Batch Number
    STBL1391
    STBL0886
    STBL0885
    STBL0452
    STBL0453

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    Inês Mesquita et al.
    Cell reports, 30(12), 4052-4064 (2020-03-27)
    Hypoxia-inducible factor-1 alpha (HIF-1α) is considered a global regulator of cellular metabolism and innate immune cell functions. Intracellular pathogens such as Leishmania have been reported to manipulate host cell metabolism. Herein, we demonstrate that myeloid cells from myeloid-restricted HIF-1α-deficient mice
    Ufuk Cobanoglu et al.
    Asian Pacific journal of cancer prevention : APJCP, 12(6), 1399-1403 (2011-12-01)
    Early diagnosis and prevention is very important for lung cancer patients. Previous studies have emphasized that the level of coenzyme Q10 (CoQ10), present primarily in mitochondria, decreases with age and is low in patients with chronic diseases. Our goal was
    R A Cunha et al.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(6), 1987-1995 (1998-05-15)
    ATP analogs substituted in the gamma-phosphorus (ATPgammaS, beta, gamma-imido-ATP, and beta,gamma-methylene-ATP) were used to probe the involvement of P2 receptors in the modulation of synaptic transmission in the hippocampus, because their extracellular catabolism was virtually not detected in CA1 slices.
    Emer P Reeves et al.
    Mycopathologia, 158(1), 73-79 (2004-10-19)
    Aspergillus fumigatus is a pathogenic fungus capable of causing both allergic lung disease and invasive aspergillosis, a serious, life-threatening condition in neutropenic patients. Aspergilli express an array of mycotoxins and enzymes which may facilitate fungal colonisation of host tissue. In
    Venkata Lokesh Battula et al.
    Haematologica, 94(2), 173-184 (2008-12-11)
    Conventionally, mesenchymal stem cells are functionally isolated from primary tissue based on their capacity to adhere to a plastic surface. This isolation procedure is hampered by the unpredictable influence of co-cultured hematopoietic and/or other unrelated cells and/or by the elimination

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