MABD83

Anti-SOX10, clone 12H6.1 Antibody

clone 12H6.1, from mouse

• Synonym(s): SOX-10
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 12H6.1, monoclonal
• species reactivity: human
• technique(s): western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_008872
• UniProt accession no.: P56693
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SOX10(6663)

Description

General description

Transcription factor SOX10 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest, glial and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Immunogen

KLH-conjugated linear peptide corresponding to Human SOX10.

Application

Detect SOX10 using this Anti-SOX10 antibody, clone 12H6.1 validated for use in western blotting.

Research Category
Stem Cell Research

Neuroscience

Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases

Quality

Evaluated by Western Blot in a SK-MEL-28 cell lysate. Western Blot Analysis: A 1:2000 dilution of this antibody detected SOX10 in a 10 µg SK-MEL-28 cell lysate.

Target description

~55 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
SK-MEL-28 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable