MAB3402C3
Anti-GFAP Antibody, Cy3 Conjugate
from mouse, CY3 conjugate
Synonym(s):
Glial fibrillary acidic protein, GFAP
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
CY3 conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
monoclonal
species reactivity
mouse, pig
species reactivity (predicted by homology)
porcine (based on 100% sequence homology), human (based on 100% sequence homology), rat (based on 100% sequence homology), chicken (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GFAP(2670)
General description
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.
Specificity
The antibody reacts with mouse GFAP. In tissue sections this
antibody stains astrocytes and Bergman glia cells (Debus, E., 1983).
antibody stains astrocytes and Bergman glia cells (Debus, E., 1983).
Immunogen
Purified glial filament protein (Debus, E., 1983).
Application
Anti-GFAP Antibody, Cy3 Conjugate is an antibody against GFAP for use in IC, IH.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected GFAP in adult mouse brain tissue.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
Quality
Evaluated by Immunocytochemistry in differentiated ReNcell VMs.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GFAP in differentiated ReNcell VMs.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GFAP in differentiated ReNcell VMs.
Target description
50 kDa Observed (Using unconjugated antibody MAB3402)
Physical form
Protein A purified
Purified mouse monoclonal IgG1 conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage and Stability
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control
Differentiated ReNcell VMs
Differentiated ReNcell VMs
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Peng Lu et al.
Investigative ophthalmology & visual science, 63(3), 18-18 (2022-03-17)
Pituitary adenylate cyclase-activating polypeptide (PACAP) has shown potent neuroprotective effects in central nervous system and retina disorders. However, whether PACAP can attenuate retinal neurodegeneration induced by acute ocular hypertension (AOH) and the underlying mechanisms remain unknown. In this study, we
Junjin Lin et al.
Scientific reports, 11(1), 23569-23569 (2021-12-09)
Microvascular compression of the trigeminal root entry zone (TREZ) is the main cause of most primary trigeminal neuralgia (TN), change of glial plasticity was previously studied in the TREZ of TN rat model induced by chronic compression. To better understand
Galina Dvoriantchikova et al.
Scientific reports, 12(1), 17152-17152 (2022-10-14)
Ischemia-reperfusion (IR) injury is implicated in a large array of pathological conditions in the retina. Increasing experimental evidence suggests that programmed necrosis makes a significant contribution to inflammation and retinal damage triggered by IR. Since there are many types of
Stephen S Dominy et al.
Science advances, 5(1), eaau3333-eaau3333 (2019-02-13)
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer's disease patients. Toxic proteases from the bacterium called gingipains were also identified in the brain of Alzheimer's patients, and levels correlated with tau and ubiquitin
Shahriar SheikhBahaei et al.
The Journal of comparative neurology, 526(13), 2032-2047 (2018-06-12)
Astrocytes, the most abundant and structurally complex glial cells of the central nervous system, are proposed to play an important role in modulating the activities of neuronal networks, including respiratory rhythm-generating circuits of the preBötzinger complex (preBötC) located in the
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service