ABN343

Anti-NIPSNAP Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Non-neuronal SNAP25-like protein, NIPSNAP1, NIPSNAP
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q9BPW8
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NIPSNAP1(8508)

Description

General description

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) brain, suggesting that NIPSNAP may play a role in memory.

Immunogen

KLH-conjugated linear peptide corresponding to human NIPSNAP.

Application

Detect the NIPSNAP protein using this Anti-NIPSNAP validated for use in WB & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected NIPSNAP in human brain tissue.

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate.

Target description

~33 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable