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Key Documents

8.53036

Sigma-Aldrich

Boc-Arg(di-Z)-OH

Novabiochem®

Synonym(s):

Boc-Arg(di-Z)-OH, N-α-Boc-N G,N G-bis-CBZ-L-arginine

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About This Item

Empirical Formula (Hill Notation):
C27H34N4O8
CAS Number:
Molecular Weight:
542.58
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)
≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

140 °C

application(s)

peptide synthesis

storage temp.

15-25°C

General description

Building block for introduction of arginine amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-12-0220

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): +14.0 - +18.0 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Protocols

The most popular reagent for cleavage of peptides from Boc-based resins is anhydrous HF. Of all the cleavage procedures HF appears to be the most versatile and least harmful to a wide variety of peptides synthesized on Boc-based resins.

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