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05-385

Sigma-Aldrich

Anti-Talin (human) Antibody, clone TA205

clone TA205, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

TA205, monoclonal

species reactivity

rabbit, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_006289

UniProt accession no.

Q9Y490

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TLN1(7094)

Specificity

Talin

Immunogen

Human Talin

Application

Anti-Talin (human) Antibody, clone TA205 is an antibody against Talin (human) for use in IP, WB, IH.
Research Category
Metabolism
Research Sub Category
Muscle Physiology

Quality

routinely evaluated by immunoblot on a human A431 RIPA cell lysate

Target description

200kDa

Linkage

Replaces: CBL227

Physical form

Format: Purified
PBS, pH 7.4, 0.05% sodium azide
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Temperature dependent specific heat capacity (Cp) of G-actin and talin or talin-vinculin bound to G-actin.
W H Goldmann et al.
Biochemical Society transactions, 20(3), 273S-273S (1992-08-01)
HSP72 inhibits apoptosis-inducing factor release in ATP-depleted renal epithelial cells.
Ruchalski, K; Mao, H; Singh, SK; Wang, Y; Mosser, DD; Li, F; Schwartz, JH; Borkan, SC
American Journal of Physiology. Cell Physiology null
Regulation of focal adhesions by flightless i involves inhibition of paxillin phosphorylation via a Rac1-dependent pathway.
Kopecki, Z; O'Neill, GM; Arkell, RM; Cowin, AJ
The Journal of Investigative Dermatology null
Hsp72 interacts with paxillin and facilitates the reassembly of focal adhesions during recovery from ATP depletion.
Mao, H; Wang, Y; Li, Z; Ruchalski, KL; Yu, X; Schwartz, JH; Borkan, SC
The Journal of Biological Chemistry null
Cécile Gaston et al.
Nature communications, 12(1), 2226-2226 (2021-04-15)
At the basis of cell shape and behavior, the organization of actomyosin and its ability to generate forces are widely studied. However, the precise regulation of this contractile network in space and time is unclear. Here, we study the role

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