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870016P

Avanti

23:2 Diyne PC [DC(8,9)PC]

Avanti Polar Lipids 870016P, powder

Synonym(s):

1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C54H92NO8P
CAS Number:
76078-28-9
Molecular Weight:
914.28
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (870016P-1g)
pkg of 1 × 200 mg (870016P-200mg)
pkg of 1 × 25 mg (870016P-25mg)
pkg of 1 × 500 mg (870016P-500mg)

manufacturer/tradename

Avanti Polar Lipids 870016P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC#CC#CCCCCCCCCCC)=O)COC(CCCCCCCCC#CC#CCCCCCCCCCC)=O)=O

InChI

1S/C54H92NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-53(56)60-50-52(51-62-64(58,59)61-49-48-55(3,4)5)63-54(57)47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h52H,6-23,32-51H2,1-5H3/t52-/m1/s1

InChI key

IDBJTPGHAMAEMV-OIVUAWODSA-N

General description

23:2 Diyne PC [DC(8,9)PC] is a chiral diynoic phosphotidylcholine (PC).

Application

23:2 Diyne PC [DC(8,9)PC] has been used in the fabrication of polydiacetylene vesicles. It has also been used in the preparation of lipid-tissue plasminogen activator (lipid-tPA) suspensions.

Packaging

20 mL Amber Glass Screw Cap Vial (870016P-1g)
20 mL Amber Glass Screw Cap Vial (870016P-500mg)
5 mL Amber Glass Screw Cap Vial (870016P-200mg)
5 mL Amber Glass Screw Cap Vial (870016P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J A Hayward et al.
Biomaterials, 5(3), 135-142 (1984-05-01)
A major restriction in the application of polymeric biomaterials is the propensity of their surfaces to support thrombosis. Theoretical approaches to the design of thromboresistant polymers have been inadequate because of the complexity of surface thrombosis. We have developed a
Amichai Yavlovich et al.
Journal of thermal analysis and calorimetry, 98(1), 97-104 (2010-02-18)
We describe a novel class of light-triggerable liposomes prepared from a photo-polymerizable phospholipid DC(8,9)PC (1,2- bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine) and DPPC (1,2-Dipalmitoyl-sn-Glycero-3-Phosphocholine). Exposure to UV (254 nm) radiation for 0-45 minutes at 25 degrees C resulted in photo-polymerization of DC(8,9)PC in these
D S Johnston et al.
Biochimica et biophysica acta, 602(1), 57-69 (1980-10-16)
A new approach has been developed for the study of model and natural biomembranes. This involves the cross-linking of diacetylene groups after ultraviolet irradiation. For the study of model biomembranes, pure phospholipids (phosphatidylcholines) have been synthesized containing diacetylene groups in
Qin Wang et al.
Journal of materials chemistry. B, 8(9), 1841-1851 (2020-02-06)
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints of the body. Although liposomes are a promising drug delivery vehicle, there is still a challenge of using conventional liposomes for the treatment of RA due
Amichai Yavlovich et al.
Biochimica et biophysica acta, 1808(1), 117-126 (2010-08-10)
Success of nanoparticle-mediated drug delivery is subject to development of optimal drug release strategies within defined space and time (triggered release). Recently, we reported a novel class of photo-triggerable liposomes prepared from dipalmitoyl phosphatidylcholine (DPPC) and photopolymerizable diacetylene phospholipid (DC(8),(9)PC)
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