850397C

20:4 (Cis) PC

1,2-diarachidonoyl-sn-glycero-3-phosphocholine, chloroform

• Synonym(s): 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; DAPC; PC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))
• Empirical Formula (Hill Notation): C₄₈H₈₀NO₈P
• CAS Number: 17688-29-8
• Molecular Weight: 830.12
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850397C-25mg); pkg of 2 × 4 mL (850397C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850397C
• concentration: 10 mg/mL (850397C-25mg); 25 mg/mL (850397C-200mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C48H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,26-29,32-35,46H,6-13,18-19,24-25,30-31,36-45H2,1-5H3/b16-14-,17-15+,22-20-,23-21-,28-26-,29-27-,34-32-,35-33-/t46-/m1/s1
• InChI key: LZLVZIFMYXDKCN-HLKGGLNDSA-N

Description

General description

20:4 (cis) PC or 1,2-diarachidonoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of arachidonic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:4 (cis) PC or 1,2-diarachidonoyl-sn-glycero-3-phosphocholine might be used:

• in lipid bilayer, to study its effect on membrane vesiculation by dynamin and endophilin
• as a phosphatidylcholine (PC) standard to compare the extraction efficiency of the three tested solvent systems prior to liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) analysis
• in low density lipid (LDL)-mimicking liposome as an alternative to LDL for evaluating the LDL-oxidation preventing antioxidants

Packaging

5 mL Clear Glass Sealed Ampule (850397C-200mg)

5 mL Clear Glass Sealed Ampule (850397C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Liver,Kidney, Respiratory system
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash