810251P

NBD-6 Cholesterol

Avanti Research^™ - A Croda Brand 810251P, powder

• Synonym(s): 5-cholesten-3β-ol 6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]caproate
• Empirical Formula (Hill Notation): C₃₉H₅₈N₄O₅
• CAS Number: 201731-19-3
• Molecular Weight: 662.90
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (810251P-1mg); pkg of 1 × 5 mg (810251P-5MG)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810251P
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

NBD-6 Cholesterol is a fluorescent analog of the lipoprotein compound cholesterol, with NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) being the fluorescent group.

Application

NBD-6 Cholesterol has been used for NBD-cholesterol binding assay, to study the binding of fluorescent NBD cholesterol in the binding pocket concerning ASTER domains.

Biochem/physiol Actions

Cholesterol is produced from acetyl-CoA by a complex multistep mevalonate pathway. In mammals, liver is the main site of de novo cholesterol synthesis contributing to almost 80% of total cholesterol synthesis. Cholesterol and its metabolites, along with its precursors, play important roles in cellular membrane physiology. They also have roles in reproductive biology, dietary nutrient absorption, stress responses, salt and water balance and calcium metabolism.

Packaging

5 mL Amber Glass Screw Cap Vial (810299P-1MG)

5 mL Amber Glass Screw Cap Vial (810251P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): No data available
• Flash Point(C): No data available