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M81101

Sigma-Aldrich

mono-Methyl hydrogen succinate

95%

Synonym(s):

Monomethyl succinate, Succinic acid monomethyl ester

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About This Item

Linear Formula:
CH3OCOCH2CH2COOH
CAS Number:
3878-55-5
Molecular Weight:
132.11
Beilstein:
1722669
EC Number:
223-408-2
MDL number:
MFCD00002788
UNSPSC Code:
12352100
PubChem Substance ID:
24897222
NACRES:
NA.22

Assay

95%

form

powder

bp

151 °C/20 mmHg (lit.)

mp

54-57 °C (lit.)

SMILES string

COC(=O)CCC(O)=O

InChI

1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)

InChI key

JDRMYOQETPMYQX-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Emma Heart et al.
The Biochemical journal, 403(1), 197-205 (2006-12-22)
The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences. Glycolysis and mitochondrial metabolism both have key
E Gottlieb et al.
Cell death and differentiation, 10(6), 709-717 (2003-05-23)
During apoptosis, the mitochondrial membrane potential (MMP) decreases, but it is not known how this relates to the apoptotic process. It was recently suggested that cytochrome c is compartmentalized in closed cristal regions and therefore, matrix remodeling is required to
C J Reid et al.
Microbiology (Reading, England), 142 ( Pt 9), 2603-2612 (1996-09-01)
Amino acid uptake by the general amino acid permease (Aap) of Rhizobium leguminosarum strain 3841 was severely reduced by the presence of aspartate in the growth medium when glucose was the carbon source. The reduction in transport by the Aap
P Maechler et al.
The Journal of biological chemistry, 274(39), 27905-27913 (1999-09-17)
The effects of a transient exposure to hydrogen peroxide (10 min at 200 microM H(2)O(2)) on pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat islets, insulin secretion evoked by glucose (16.7 mM) or by the
L Ladrière et al.
Annals of nutrition & metabolism, 41(2), 118-125 (1997-01-01)
Rats were fasted for 48 h, but infused with either NaCl or the sodium salt of monoethyl succinic acid (EMS), both delivered at a rate of 80 mumol/g body weight per day. The infusion of EMS, as compared to NaCl
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