861545

N¹⁰-(Trifluoroacetyl)pteroic acid

95%

• Synonym(s): 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]benzoic acid, N10-Trifluoroacetylpteroic acid
• Empirical Formula (Hill Notation): C₁₆H₁₁F₃N₆O₄
• CAS Number: 37793-53-6
• Molecular Weight: 408.29
• MDL number: MFCD00006707
• UNSPSC Code: 12352100
• PubChem Substance ID: 24888548
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 95%
• form: solid
• mp: 270 °C (dec.) (lit.)
• functional group: amide; carboxylic acid; fluoro
• SMILES string: Nc1nc(O)c2nc(CN(c3ccc(cc3)C(O)=O)C(=O)C(F)(F)F)cnc2n1
• InChI: 1S/C16H11F3N6O4/c17-16(18,19)14(29)25(9-3-1-7(2-4-9)13(27)28)6-8-5-21-11-10(22-8)12(26)24-15(20)23-11/h1-5H,6H2,(H,27,28)(H3,20,21,23,24,26)
• InChI key: IJGIHDXKYQLIMA-UHFFFAOYSA-N

Description

Application

N¹⁰-(Trifluoroacetyl)pteroic acid is a structural component of folic acid. It can be used as a precursor to synthesize folic acid derivatives, γ-azido modified folic acid, and pteroyl-γ-glutamate-cysteine.

Other Notes

Remainder DMF

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H315,H319,H335,H350
• Precautionary Statements: P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves