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Merck

MRPS15

mitochondrial ribosomal protein S15

Synonyms:
MPR-S15, RPMS15, S15mt
Species:
UniProtKB ID:
Gene ID:
  • Human(64960) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q. [provided by RefSeq, Jul 2008]
  • Mouse(66407) mitochondrial ribosomal protein S15
  • Rat(298517) mitochondrial ribosomal protein S15
  • Zebrafish(436758) mitochondrial ribosomal protein S15
  • cow(508928) mitochondrial ribosomal protein S15
  • domestic cat(101089535) mitochondrial ribosomal protein S15
  • dog(475333) mitochondrial ribosomal protein S15
  • chicken(770261) mitochondrial ribosomal protein S15
  • sheep(101113805) mitochondrial ribosomal protein S15
  • naked mole-rat(101725042) mitochondrial ribosomal protein S15
  • domestic guinea pig(100719880) mitochondrial ribosomal protein S15

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRPS15 Antibody, clone 8Q8T5, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mrps15,
Species
mouse
MISSION® esiRNA, targeting human MRPS15,
Species
human