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COO/COA

Glycerol

Name: Glycerol
Brand: SIGMA

for molecular biology, ≥99.0%

Synonym(s):

1,2,3-Propanetriol, Glycerin

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About This Item

Linear Formula:

HOCH₂CH(OH)CH₂OH

CAS Number:

56-81-5

Molecular Weight:

92.09

Beilstein/REAXYS Number:

635685

EC Number:

200-289-5

MDL number:

MFCD00004722

UNSPSC Code:

50161901

PubChem Substance ID:

24895216

NACRES:

NA.31

grade

for molecular biology
reagent

Quality Level

200

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

assay

≥99.0%

form

viscous liquid

autoignition temp.

698 °F

expl. lim.

≥2.7-19.0 %

technique(s)

MALDI-MS: suitable
cryopreservation: suitable

impurities

<5 ppm Iron
<5 ppm heavy metal
<5 ppm magnesium

refractive index

n20/D 1.474 (lit.)

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

solubility

water: 1 mL/mL, clear, colorless

density

1.25 g/mL (lit.)

cation traces

Fe: ≤5 ppm
Mg: ≤5 ppm
heavy metals (as Pb): <5 ppm

application(s)

life science and biopharma
microbiology
sample preservation

foreign activity

DNase, RNase, NICKase, and protease, none detected

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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General description

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Application

Glycerol has been used as:

a component of mounting medium for immunofluorescence
a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
a fuel during the designing of enzymatic biofuel cells.
a liquid composite matrix with 4-HCCA and 3-aminoquinoline for analysis of neutral and acidic glycans.
a matrix for fast atom bombardment MS.

Glycerol may be employed as a liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Biochem/physiol Actions

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Features and Benefits

This product has been analyzed for the presence of nucleases and proteases.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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