VPS72
vacuolar protein sorting 72 homolog (S. cerevisiae)
Synonyms:
CFL1, Swc2, TCFL1, YL-1, YL1
Species:
Human VPS72 (6944), Mouse Vps72 (21427), Rat Vps72 (310661), Zebrafish vps72 (100001285), chicken VPS72 (425660), dog VPS72 (475843), Horse VPS72 (100147071), domestic cat VPS72 (101097749), domestic guinea pig Vps72 (100713883), naked mole-rat Vps72 (101704477) ...More
UniProtKB ID:
Gene ID:
- Human(6944) Summary: The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
- Mouse(21427) vacuolar protein sorting 72 (yeast)
- Rat(310661) vacuolar protein sorting 72 homolog (S. cerevisiae)
- Zebrafish(100001285) vacuolar protein sorting 72 homolog (S. cerevisiae)
- chicken(425660) vacuolar protein sorting 72 homolog (S. cerevisiae)
- dog(475843) vacuolar protein sorting 72 homolog (S. cerevisiae)
- Horse(100147071) vacuolar protein sorting 72 homolog (S. cerevisiae)
- domestic cat(101097749) vacuolar protein sorting 72 homolog (S. cerevisiae)
- domestic guinea pig(100713883) vacuolar protein sorting 72 homolog (S. cerevisiae)
- naked mole-rat(101704477) vacuolar protein sorting 72 homolog (S. cerevisiae)
- Domestic Rabbit(100328667) vacuolar protein sorting 72 homolog (S. cerevisiae)
- cow(534883) vacuolar protein sorting 72 homolog (S. cerevisiae)
- sheep(101113547) vacuolar protein sorting 72 homolog (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-VPS72 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence