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TNFRSF11A

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Synonyms:
CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Species:
UniProtKB ID:
Gene ID:
  • Human(8792) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
  • Mouse(21934) tumor necrosis factor receptor superfamily, member 11a
  • Rat(498206) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • cow(530884) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • sheep(101118842) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • naked mole-rat(101718050) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • Domestic Rabbit(100358260) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • domestic guinea pig(100724119) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • chicken(769909) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • dog(483957) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • domestic cat(101090651) tumor necrosis factor receptor superfamily, member 11a, NFKB activator

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ELISA

Product Number
Description
Species
Human TNFRSF11A ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TNFRSF11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-TNFRSF11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
RANK/Fc Chimera from mouse, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
mouse
sRank Receptor human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human