SCN1B
sodium channel, voltage-gated, type I, beta subunit
Synonyms:
ATFB13, BRGDA5, GEFSP1
Species:
Human SCN1B (6324), Mouse Scn1b (20266), Rat Scn1b (29686), cow SCN1B (618204), sheep SCN1B (101123143), naked mole-rat Scn1b (101709080), Domestic Rabbit SCN1B (100009211), domestic guinea pig Scn1b (100718757), domestic cat SCN1B (101101526), dog SCN1B (484584)
UniProtKB ID:
Gene ID:
- Human(6324) Summary: Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(20266) sodium channel, voltage-gated, type I, beta
- Rat(29686) sodium channel, voltage-gated, type I, beta
- cow(618204) sodium channel, voltage-gated, type I, beta subunit
- sheep(101123143) sodium channel, voltage-gated, type I, beta subunit
- naked mole-rat(101709080) sodium channel, voltage-gated, type I, beta subunit
- Domestic Rabbit(100009211) sodium channel, voltage-gated, type I, beta subunit
- domestic guinea pig(100718757) sodium channel, voltage-gated, type I, beta subunit
- domestic cat(101101526) sodium channel, voltage-gated, type I, beta subunit
- dog(484584) sodium channel, voltage-gated, type I, beta subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SCN1B, affinity isolated antibody,
Species Reactivity
dog, guinea pig, human, rabbit, rat
Application
western blot