MEP1B
meprin A, beta
Synonyms:
Species:
Human MEP1B (4225), Mouse Mep1b (17288), Rat Mep1b (25727), Zebrafish mep1b (100151009), chicken MEP1B (421097), cow MEP1B (540701), Horse MEP1B (100052389), domestic cat MEP1B (101089149), dog MEP1B (490497), domestic guinea pig Mep1b (100733995) ...More
UniProtKB ID:
Gene ID:
- Human(4225) Summary: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
- Mouse(17288) meprin 1 beta
- Rat(25727) meprin 1 beta
- Zebrafish(100151009) meprin A, beta
- chicken(421097) meprin A, beta
- cow(540701) meprin A, beta
- Horse(100052389) meprin A, beta
- domestic cat(101089149) meprin A, beta
- dog(490497) meprin A, beta
- domestic guinea pig(100733995) meprin A, beta
- Domestic Rabbit(100349918) meprin A, beta
- naked mole-rat(101721966) meprin A, beta
- sheep(101114072) meprin A, beta
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MEP1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry