LIFR
leukemia inhibitory factor receptor alpha
Synonyms:
CD118, LIF-R, SJS2, STWS, SWS
Species:
Human LIFR (3977), Mouse Lifr (16880), Rat Lifr (81680), sheep LIFR (101106364), Domestic Rabbit LIFR (100303762), domestic guinea pig Lifr (100716454), naked mole-rat Lifr (101696861), chicken LIFR (395262), dog LIFR (449478), cow LIFR (539504)
UniProtKB ID:
Gene ID:
- Human(3977) Summary: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16880) leukemia inhibitory factor receptor
- Rat(81680) leukemia inhibitory factor receptor alpha
- sheep(101106364) leukemia inhibitory factor receptor alpha
- Domestic Rabbit(100303762) leukemia inhibitory factor receptor alpha
- domestic guinea pig(100716454) leukemia inhibitory factor receptor alpha
- naked mole-rat(101696861) leukemia inhibitory factor receptor alpha
- chicken(395262) leukemia inhibitory factor receptor alpha
- dog(449478) leukemia inhibitory factor receptor alpha
- cow(539504) leukemia inhibitory factor receptor alpha
- domestic cat(101097206) leukemia inhibitory factor receptor alpha
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LIF Receptor, clone 1C7 (Azide Free) Antibody, clone 1C7, from mouse,
Species Reactivity
human
Application
flow cytometry
inhibition assay
inhibition assay
Anti-LIFR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species