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Merck

IGFBP7

insulin-like growth factor binding protein 7

Synonyms:
AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF
Species:
UniProtKB ID:
Gene ID:
  • Human(3490) Summary: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
  • Mouse(29817) insulin-like growth factor binding protein 7
  • Rat(289560) insulin-like growth factor binding protein 7
  • Zebrafish(405860) insulin-like growth factor binding protein 7
  • domestic cat(101083263) insulin-like growth factor binding protein 7
  • cow(616368) insulin-like growth factor binding protein 7
  • dog(608559) insulin-like growth factor binding protein 7
  • chicken(422620) insulin-like growth factor binding protein 7
  • domestic guinea pig(100731297) insulin-like growth factor binding protein 7
  • naked mole-rat(101717990) insulin-like growth factor binding protein 7
  • sheep(100270713) insulin-like growth factor binding protein 7

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IGFBP7 Antibody, clone 8M10Q9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
IGF-Binding Protein 7 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human
SILuProt IGFBP7 Insulin-like growth factor-binding protein 7 human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human
SILuLite IGFBP7 Insulin-like growth factor-binding protein 7 human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Igfbp7,
Species
mouse
MISSION® esiRNA, targeting human IGFBP7,
Species
human