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Merck

ICK

intestinal cell (MAK-like) kinase

Synonyms:
ECO, LCK2, MRK
Species:
UniProtKB ID:
Gene ID:
  • Human(22858) Summary: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(56542) intestinal cell kinase
  • Rat(84411) intestinal cell kinase
  • sheep(101107478) intestinal cell (MAK-like) kinase
  • domestic guinea pig(100731366) intestinal cell (MAK-like) kinase
  • naked mole-rat(101715354) intestinal cell (MAK-like) kinase
  • chicken(421896) intestinal cell (MAK-like) kinase
  • domestic cat(101085288) intestinal cell (MAK-like) kinase
  • cow(506286) intestinal cell (MAK-like) kinase
  • Horse(100056645) intestinal cell (MAK-like) kinase
  • dog(481843) intestinal cell (MAK-like) kinase

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-ICK (pTyr159) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ICK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ICK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ICK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ick,
Species
mouse
MISSION® esiRNA, targeting human ICK,
Species
human