F7
coagulation factor VII (serum prothrombin conversion accelerator)
Synonyms:
SPCA
Species:
Human F7 (2155), Mouse F7 (14068), Rat F7 (260320), sheep F7 (101118369), Domestic Rabbit F7 (100009399), naked mole-rat F7 (101706917), domestic guinea pig F7 (100727155), Zebrafish f7 (114423), cow F7 (617960), domestic cat F7 (101090581) ...More
UniProtKB ID:
Gene ID:
- Human(2155) Summary: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- Mouse(14068) coagulation factor VII
- Rat(260320) coagulation factor VII (serum prothrombin conversion accelerator)
- sheep(101118369) coagulation factor VII (serum prothrombin conversion accelerator)
- Domestic Rabbit(100009399) coagulation factor VII (serum prothrombin conversion accelerator)
- naked mole-rat(101706917) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic guinea pig(100727155) coagulation factor VII (serum prothrombin conversion accelerator)
- Zebrafish(114423) coagulation factor VII
- cow(617960) coagulation factor VII (serum prothrombin conversion accelerator)
- domestic cat(101090581) coagulation factor VII (serum prothrombin conversion accelerator)
- dog(607661) coagulation factor VII (serum prothrombin conversion accelerator)
- fruit fly(5657732) f7
- chicken(395086) coagulation factor VII (serum prothrombin conversion accelerator)
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ELISA
Product Number
Description
Species
Human Coagulation Factor VII ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Factor VII antibody, Mouse monoclonal, clone HVII-1, purified from hybridoma cell culture,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-FA7 (light chain, Cleaved-Arg212) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-F7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
western blot
Anti-Coagulation factor VIIa, from rabbit, purified by affinity chromatography,
Species Reactivity
human, primate
Application
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot