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Merck

CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

别名:
CPN1, CYP11B, FHI, P450C11
物种:
Human CYP11B1 (1584), Mouse Cyp11b1 (110115), Rat Cyp11b1 (500892), domestic guinea pig Cyp11b1 (100135511), sheep CYP11B1 (767576), cow CYP11B1 (282422)
UniProtKB ID:
P15538, Q14095, Q4VAQ8, Q4VAQ9, Q9UML2
基因ID:
  • Human(1584) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(110115) cytochrome P450, family 11, subfamily b, polypeptide 1
  • Rat(500892) cytochrome P450, family 11, subfamily b, polypeptide 1
  • domestic guinea pig(100135511) cytochrome P450, family 11, subfamily b, polypeptide 1
  • sheep(767576) cytochrome P450, family 11, subfamily B, polypeptide 1
  • cow(282422) cytochrome P450, subfamily XI B, polypeptide 1

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Antibodies

货号
说明
物种反应性
应用
ZRB2564
Anti-CYP11B1 Antibody, clone 1J14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
MABS502
抗-CYP11B1抗体，克隆80-7, clone 80-7, from rat,
物种反应性
human, rat
应用
immunohistochemistry
western blot
HPA056348
Anti-CYP11B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
MAB6020
Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon®,
物种反应性
rat
应用
immunohistochemistry
western blot
SAB1303151
ANTI-CYP11B1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
1445007
线粒体, United States Pharmacopeia (USP) Reference Standard,
物种
human
35485
2,4′-DDD, PESTANAL®, analytical standard,
物种
human
44012
1-(2-氯苯基)-1-(4-氯苯基)-2,2-二氯乙烷, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
物种
human
K1003
酮康唑, 99.0-101.0% (EP, titration),
物种
mouse, human, rat

esiRNA

货号
说明
物种
EHU140441
MISSION® esiRNA, targeting human CYP11B1,
物种
human