CREBL2
cAMP responsive element binding protein-like 2
Synonyms:
Species:
Human CREBL2 (1389), Mouse Crebl2 (232430), Rat Crebl2 (362453), Zebrafish crebl2 (436975), dog CREBL2 (611207), cow CREBL2 (537195), domestic cat CREBL2 (101092030), chicken CREBL2 (426496), sheep CREBL2 (101112213), domestic guinea pig Crebl2 (100736119)
UniProtKB ID:
Gene ID:
- Human(1389) Summary: cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Mouse(232430) cAMP responsive element binding protein-like 2
- Rat(362453) cAMP responsive element binding protein-like 2
- Zebrafish(436975) cAMP responsive element binding protein-like 2
- dog(611207) cAMP responsive element binding protein-like 2
- cow(537195) cAMP responsive element binding protein-like 2
- domestic cat(101092030) cAMP responsive element binding protein-like 2
- chicken(426496) cAMP responsive element binding protein-like 2
- sheep(101112213) cAMP responsive element binding protein-like 2
- domestic guinea pig(100736119) cAMP responsive element binding protein-like 2
- naked mole-rat(101699677) cAMP responsive element binding protein-like 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CREBL2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot