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Merck

CCR3

chemokine (C-C motif) receptor 3

Synonyms:
CC-CKR-3, CD193, CKR3, CMKBR3
Species:
UniProtKB ID:
Gene ID:
  • Human(1232) Summary: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
  • Mouse(12771) chemokine (C-C motif) receptor 3
  • Rat(117027) chemokine (C-C motif) receptor 3
  • Thale Cress(824761) CRINKLY4 related 3
  • cow(408018) chemokine (C-C motif) receptor 3
  • dog(448802) chemokine (C-C motif) receptor 3
  • domestic cat(100191005) chemokine (C-C motif) receptor 3
  • sheep(443111) chemokine (C-C motif) receptor 3
  • Domestic Rabbit(100189557) chemokine (C-C motif) receptor 3
  • naked mole-rat(101724462) chemokine (C-C motif) receptor 3
  • domestic guinea pig(100135496) chemokine (C-C motif) receptor 3
  • domestic guinea pig(100718618) chemokine (C-C motif) receptor 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CCR3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CCR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CCR3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CCR3 antibody produced in rabbit, affinity purified immunoglobulin (IgG),
Species Reactivity
Application
western blot
Monoclonal Anti-CD193 antibody produced in mouse, clone 5E8,
Species Reactivity
human
Application
flow cytometry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCR3,
Species
human