CCR1
chemokine (C-C motif) receptor 1
Synonyms:
CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Species:
Human CCR1 (1230), Mouse Ccr1 (12768), Rat Ccr1 (57301), Thale Cress CCR1 (820136), cow CCR1 (407771), domestic cat CCR1 (100191004), Thale Cress CCR1 (830082), Thale Cress CCR1 (838165), dog CCR1 (484791), naked mole-rat Ccr1 (101724812) ...More
UniProtKB ID:
Gene ID:
- Human(1230) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
- Mouse(12768) chemokine (C-C motif) receptor 1
- Rat(57301) chemokine (C-C motif) receptor 1
- Thale Cress(820136) serine/threonine-protein kinase-like protein CCR1
- cow(407771) chemokine (C-C motif) receptor 1
- domestic cat(100191004) chemokine (C-C motif) receptor 1
- Thale Cress(830082) glycine-rich RNA-binding protein 8
- Thale Cress(838165) cinnamoyl coa reductase 1
- dog(484791) chemokine (C-C motif) receptor 1
- naked mole-rat(101724812) chemokine (C-C motif) receptor 1
- domestic guinea pig(100716398) chemokine (C-C motif) receptor 1
- Domestic Rabbit(100328940) chemokine (C-C motif) receptor 1
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Small Molecule - Antagonist
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Description
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Proteins
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Description
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ChemiSCREEN CCR1 Membrane Preparation, Human CCR1 GPCR membrane preparation for Radioligand binding Assays.,
Species
human
esiRNA
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