KLC1
kinesin light chain 1
KLC, KNS2, KNS2A
Human KLC1 (3831), Mouse Klc1 (16593), Rat Klc1 (171041), chicken KLC1 (423484), cow KLC1 (508999), Horse KLC1 (100055290), domestic cat KLC1 (101099130), dog KLC1 (480446), sheep KLC1 (101102677), domestic guinea pig Klc1 (100736081)
- Human(3831) Summary: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
- Mouse(16593) kinesin light chain 1
- Rat(171041) kinesin light chain 1
- chicken(423484) kinesin light chain 1
- cow(508999) kinesin light chain 1
- Horse(100055290) kinesin light chain 1
- domestic cat(101099130) kinesin light chain 1
- dog(480446) kinesin light chain 1
- sheep(101102677) kinesin light chain 1
- domestic guinea pig(100736081) kinesin light chain 1
- naked mole-rat(101710626) kinesin light chain 1
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Antibodies
Anti-KLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-KLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
ANTI-KLC1 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
human
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Kinesin light chain 1 (KLC1) Antibody, clone 5C3P5, Rabbit Monoclonal, ,
human, rat
western blot
Anti-Kinesin Antibody, light chain, clone L2, clone L2, Chemicon®, from mouse,
mammals
ELISA
immunoprecipitation (IP)
radioimmunoassay
western blot
immunoprecipitation (IP)
radioimmunoassay
western blot