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Merck

The metabolism of ethosuximide.

European journal of drug metabolism and pharmacokinetics (1993-10-01)
J S Millership, J Mifsud, P S Collier
PMID8020533
ABSTRACT

The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.

MATERIALS
Product Number
Brand
Product Description
E7138
Sigma-Aldrich
Ethosuximide
E2150000
Ethosuximide, European Pharmacopoeia (EP) Reference Standard
68459
Supelco
Ethosuximide, analytical standard
PHR1413
Supelco
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material