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Merck

Chromium and genomic stability.

Mutation research (2011-12-24)
Sandra S Wise, John Pierce Wise
ABSTRACT

Many metals serve as micronutrients which protect against genomic instability. Chromium is most abundant in its trivalent and hexavalent forms. Trivalent chromium has historically been considered an essential element, though recent data indicate that while it can have pharmacological effects and value, it is not essential. There is no data indicating that trivalent chromium promotes genomic stability and, instead may promote genomic instability. Hexavalent chromium is widely accepted as highly toxic and carcinogenic with no nutritional value. Recent data indicate that it causes genomic instability and also has no role in promoting genomic stability.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Chromium, sputtering target, diam. × thickness 3.00 in. × 0.125 in., 99.95% trace metals basis
Sigma-Aldrich
Chromium, chips, thickness ~2 mm, 99.5%
Sigma-Aldrich
Chromium, powder, 99.5%, −100 mesh
Sigma-Aldrich
Chromium, powder, ≥99% trace metals basis, <45 μm
Sigma-Aldrich
Chromium, chips, 99.995% trace metals basis