Synthesis of N-[3,4-dimethoxyphenyl)propanoyl]pyrrole, a metabolite of Piper brachystachyum.

Synthesis of N-[3,4-dimethoxyphenyl)propanoyl]pyrrole, a metabolite of Piper brachystachyum.

Journal of Asian natural products research (2001-03-17)

J Kavitha, G V Subbaraju

ABSTRACT

N-[3-(3,4-Dimethoxyphenyl)propanoyl]pyrrole (1) has been synthesized in three steps starting from veratraldehyde (2) with an overall yield of 66%.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Veratraldehyde, ≥98%, FG

Sigma-Aldrich

3,4-Dimethoxybenzaldehyde, 99%

Supelco

Verapamil Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material