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Key Documents

269A-1

Sigma-Aldrich

IgG Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (269A-14)
vial of 0.5 mL concentrate (269A-15)
bottle of 1.0 mL predilute (269A-17)
vial of 1.0 mL concentrate (269A-16)
bottle of 7.0 mL predilute (269A-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, membranous

General description

Anti-IgG antibody reacts with surface immunoglobulin IgG gamma chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived Hodgkin′s lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell lymphomas is possible with clonal gene rearrangement studies.

Quality


IVD
IVD
IVD
RUO

Linkage

IgG (polyclonal) Positive Control Slides, Product No. 269S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

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U Schmid et al.
The American journal of surgical pathology, 19(1), 12-20 (1995-01-01)
Twenty cases of cutaneous follicular lymphoid hyperplasia with monotypic plasma cells are presented in a clinicopathologic study on 18 patients. The plaque-like or nodular lesions were solitary in 10 and multiple in eight patients. Immunohistochemistry showed well-defined B- and T-cell
K Ando et al.
Internal medicine (Tokyo, Japan), 39(2), 170-175 (2000-03-25)
A 72-year-old man was admitted to our hospital because of lumbago and numbness of legs. Tumor invasion at the fourth lumbar vertebra was revealed. Immunohistochemistry using specific antibodies against each heavy and light chain of immunoglobulin revealed that the myeloma
Manual of Diagnostic Antibodies for Immunohistology, 217-219 (1999)
Tissue section immunologic methods in lymphomas
Warnake, R., et al.
Diagnostic Immunohistochemistry (Masson Publishing), 203-221 (1981)
A Arnold et al.
The New England journal of medicine, 309(26), 1593-1599 (1983-12-29)
Immunoglobulin genes in their germ-line form are separated DNA subsegments that must be joined by means of recombinations during B-cell development. Individual immunoglobulin-gene rearrangements are specific for a given B cell and its progeny. We show that the detection of
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