03-34-0002

H-Arg-Gly-Asp-Ser-OH

• Synonym(s): H-Arg-Gly-Asp-Ser-OH, Fibronectin Inhibitor, RGDS
• Empirical Formula (Hill Notation): C₁₅H₂₇N₇O₈
• CAS Number: 91037-65-9
• Molecular Weight: 433.42
• MDL number: MFCD00076452
• UNSPSC Code: 12352202

Properties

• Assay: ≥97% (HPLC)
• Quality Level: 100
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white to off-white
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1
• InChI key: NNRFRJQMBSBXGO-CIUDSAMLSA-N

Description

General description

Shown to inhibit fibronectin function by binding to platelet-binding sites.

Biochem/physiol Actions

Cell permeable: no

Primary Target
fibronectin

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Perlot, R.L., et al. 2002. J. Bone Miner. Res.17, 66.
Ginsberg, M., et al. 1985. J. Biol. Chem.260, 3931.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable