VPS37A
vacuolar protein sorting 37 homolog A (S. cerevisiae)
HCRP1, PQBP2, SPG53
Human VPS37A (137492), Mouse Vps37a (52348), Rat Vps37a (290775), Zebrafish vps37a (336368), Horse VPS37A (100050168), domestic cat VPS37A (101083260), dog VPS37A (475611), chicken VPS37A (422732), cow VPS37A (513985), sheep VPS37A (101120049) ...More
- Human(137492) Summary: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
- Mouse(52348) vacuolar protein sorting 37A (yeast)
- Rat(290775) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- Zebrafish(336368) vacuolar protein sorting 37A
- Horse(100050168) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- domestic cat(101083260) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- dog(475611) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- chicken(422732) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- cow(513985) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- sheep(101120049) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- naked mole-rat(101700435) vacuolar protein sorting 37 homolog A (S. cerevisiae)
- domestic guinea pig(100732379) vacuolar protein sorting 37 homolog A (S. cerevisiae)
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