USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Synonyms:
TGT
Species:
Human USP14 (9097), Mouse Usp14 (59025), Rat Usp14 (291796), Domestic Rabbit USP14 (100009078), naked mole-rat Usp14 (101710957), domestic guinea pig Usp14 (100719247), cow USP14 (505106), sheep USP14 (101121734), Zebrafish usp14 (335736), domestic cat USP14 (101091976) ...More
UniProtKB ID:
Gene ID:
- Human(9097) Summary: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(59025) ubiquitin specific peptidase 14
- Rat(291796) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- Domestic Rabbit(100009078) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- naked mole-rat(101710957) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- domestic guinea pig(100719247) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- cow(505106) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- sheep(101121734) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- Zebrafish(335736) ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
- domestic cat(101091976) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- dog(480182) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- chicken(421063) ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-USP14 antibody produced in mouse, clone 6D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot