UBB
ubiquitin B
Synonyms:
Species:
Human UBB (7314), Mouse Ubb (22187), Rat Ubb (192255), cow UBB (281370), naked mole-rat Ubb (101702552), domestic guinea pig Ubb (100722422), Zebrafish ubb (550134), chicken UBB (396190), Horse UBB (100049794), domestic cat UBB (101091319)
UniProtKB ID:
Gene ID:
- Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
- Mouse(22187) ubiquitin B
- Rat(192255) ubiquitin B
- cow(281370) ubiquitin B
- naked mole-rat(101702552) ubiquitin B
- domestic guinea pig(100722422) ubiquitin B
- Zebrafish(550134) ubiquitin B
- chicken(396190) ubiquitin B
- Horse(100049794) ubiquitin B
- domestic cat(101091319) ubiquitin B
- dog(479513) ubiquitin B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Ubiquitin Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
drosophila, e. coli, bovine, canine, chicken, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast
Application
Anti-UBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-UBB antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Ubiquitin antibody produced in rabbit, whole antiserum, lyophilized powder,
Species Reactivity
eukaryotes, prokaryotes
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-Ubiquitin antibody produced in mouse, clone 6C1, ascites fluid,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
microarray
western blot
microarray
western blot