TRAF3IP2
TRAF3 interacting protein 2
Synonyms:
ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, PSORS13
Species:
Human TRAF3IP2 (10758), Mouse Traf3ip2 (103213), Rat Traf3ip2 (361857), Zebrafish traf3ip2 (386940), chicken TRAF3IP2 (421752), Horse TRAF3IP2 (100066812), domestic cat TRAF3IP2 (101085125), dog TRAF3IP2 (475031), naked mole-rat Traf3ip2 (101721876), Domestic Rabbit TRAF3IP2 (100338995) ...More
UniProtKB ID:
Gene ID:
- Human(10758) Summary: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]
- Mouse(103213) TRAF3 interacting protein 2
- Rat(361857) Traf3 interacting protein 2
- Zebrafish(386940) TRAF3 interacting protein 2
- chicken(421752) TRAF3 interacting protein 2
- Horse(100066812) TRAF3 interacting protein 2
- domestic cat(101085125) TRAF3 interacting protein 2
- dog(475031) TRAF3 interacting protein 2
- naked mole-rat(101721876) TRAF3 interacting protein 2
- Domestic Rabbit(100338995) TRAF3 interacting protein 2
- domestic guinea pig(100728787) TRAF3 interacting protein 2
- cow(616801) TRAF3 interacting protein 2
- sheep(101109809) TRAF3 interacting protein 2
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