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Merck

TP63

tumor protein p63

Synonyms:
AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
Species:
Human TP63 (8626), Rat Tp63 (246334), cow TP63 (615335), sheep TP63 (101108874), sheep TP63 (100048992), domestic guinea pig Tp63 (100732143), naked mole-rat Tp63 (101710600), Zebrafish tp63 (260407), Horse TP63 (100059752), domestic cat TP63 (101095124) ...More
UniProtKB ID:
Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4
Gene ID:
  • Human(8626) Summary: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]
  • Rat(246334) tumor protein p63
  • cow(615335) tumor protein p63
  • sheep(101108874) tumor protein p63
  • sheep(100048992) tumor protein p63
  • domestic guinea pig(100732143) tumor protein p63
  • naked mole-rat(101710600) tumor protein p63
  • Zebrafish(260407) tumor protein p63
  • Horse(100059752) tumor protein p63
  • domestic cat(101095124) tumor protein p63
  • chicken(374269) tumor protein p63
  • dog(488125) tumor protein p63

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2701838
Anti-tp63 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
zebrafish
Application
immunohistochemistry
western blot
SAB2106321
Anti-TRP63 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, rabbit, rat
Application
western blot

Proteins

Product Number
Description
Species
SRP5112
p63, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human