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Merck

TNFRSF8

tumor necrosis factor receptor superfamily, member 8

Synonyms:
CD30, D1S166E, Ki-1
Species:
Human TNFRSF8 (943), Mouse Tnfrsf8 (21941), Rat Tnfrsf8 (25069), cow TNFRSF8 (614780), sheep TNFRSF8 (101111039), domestic guinea pig Tnfrsf8 (100723547), naked mole-rat Tnfrsf8 (101704995), chicken TNFRSF8 (395090), dog TNFRSF8 (487438), domestic cat TNFRSF8 (101101575)
UniProtKB ID:
P28908, B1AN79, Q6P4D9
Gene ID:
  • Human(943) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(21941) tumor necrosis factor receptor superfamily, member 8
  • Rat(25069) tumor necrosis factor receptor superfamily, member 8
  • cow(614780) tumor necrosis factor receptor superfamily, member 8
  • sheep(101111039) tumor necrosis factor receptor superfamily, member 8
  • domestic guinea pig(100723547) tumor necrosis factor receptor superfamily, member 8
  • naked mole-rat(101704995) tumor necrosis factor receptor superfamily, member 8
  • chicken(395090) tumor necrosis factor receptor superfamily, member 8
  • dog(487438) tumor necrosis factor receptor superfamily, member 8
  • domestic cat(101101575) tumor necrosis factor receptor superfamily, member 8
  • Horse(100055885) tumor necrosis factor receptor superfamily, member 8

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