TIMP2
TIMP metallopeptidase inhibitor 2
Synonyms:
CSC-21K, DDC8
Species:
Human TIMP2 (7077), Mouse Timp2 (21858), Rat Timp2 (29543), chicken TIMP2 (374178), dog TIMP2 (403633), Horse TIMP2 (100034134), domestic cat TIMP2 (101083125), domestic guinea pig Timp2 (100135629), naked mole-rat Timp2 (101707659), Domestic Rabbit TIMP2 (100008689) ...More
UniProtKB ID:
Gene ID:
- Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
- Mouse(21858) tissue inhibitor of metalloproteinase 2
- Rat(29543) TIMP metallopeptidase inhibitor 2
- chicken(374178) TIMP metallopeptidase inhibitor 2
- dog(403633) TIMP metallopeptidase inhibitor 2
- Horse(100034134) TIMP metallopeptidase inhibitor 2
- domestic cat(101083125) TIMP metallopeptidase inhibitor 2
- domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
- naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
- Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
- cow(282093) TIMP metallopeptidase inhibitor 2
- sheep(100217406) TIMP metallopeptidase inhibitor 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Tissue Inhibitor of Metalloproteinase-2, First Loop antibody produced in rabbit, ~1 mg/mL, buffered aqueous glycerol solution, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-TIMP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-TIMP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
western blot