STAT4
signal transducer and activator of transcription 4
Synonyms:
SLEB11
Species:
Human STAT4 (6775), Mouse Stat4 (20849), Rat Stat4 (367264), Zebrafish stat4 (368519), chicken STAT4 (768406), dog STAT4 (478845), domestic cat STAT4 (101080650), Horse STAT4 (100054693), domestic guinea pig Stat4 (100726892), Domestic Rabbit STAT4 (100344146) ...More
UniProtKB ID:
Gene ID:
- Human(6775) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
- Mouse(20849) signal transducer and activator of transcription 4
- Rat(367264) signal transducer and activator of transcription 4
- Zebrafish(368519) signal transducer and activator of transcription 4
- chicken(768406) signal transducer and activator of transcription 4
- dog(478845) signal transducer and activator of transcription 4
- domestic cat(101080650) signal transducer and activator of transcription 4
- Horse(100054693) signal transducer and activator of transcription 4
- domestic guinea pig(100726892) signal transducer and activator of transcription 4
- Domestic Rabbit(100344146) signal transducer and activator of transcription 4
- naked mole-rat(101718558) signal transducer and activator of transcription 4
- cow(515988) signal transducer and activator of transcription 4
- sheep(101117562) signal transducer and activator of transcription 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-STAT4 (pTyr693) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-STAT4 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, pig, rabbit
Application
immunohistochemistry
western blot
western blot