SPTLC1
serine palmitoyltransferase, long chain base subunit 1
Synonyms:
HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
Species:
Human SPTLC1 (10558), Mouse Sptlc1 (268656), Rat Sptlc1 (361213), Zebrafish sptlc1 (553981), chicken SPTLC1 (426145), domestic cat SPTLC1 (101087947), dog SPTLC1 (484192), cow SPTLC1 (614165), sheep SPTLC1 (101105721), Domestic Rabbit SPTLC1 (100344536) ...More
UniProtKB ID:
Gene ID:
- Human(10558) Summary: Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(268656) serine palmitoyltransferase, long chain base subunit 1
- Rat(361213) serine palmitoyltransferase, long chain base subunit 1
- Zebrafish(553981) serine palmitoyltransferase, long chain base subunit 1
- chicken(426145) serine palmitoyltransferase, long chain base subunit 1
- domestic cat(101087947) serine palmitoyltransferase, long chain base subunit 1
- dog(484192) serine palmitoyltransferase, long chain base subunit 1
- cow(614165) serine palmitoyltransferase, long chain base subunit 1
- sheep(101105721) serine palmitoyltransferase, long chain base subunit 1
- Domestic Rabbit(100344536) serine palmitoyltransferase, long chain base subunit 1
- naked mole-rat(101716616) serine palmitoyltransferase, long chain base subunit 1
- domestic guinea pig(100726468) serine palmitoyltransferase, long chain base subunit 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-SPTLC1, (C-terminal) antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot