SOCS1
suppressor of cytokine signaling 1
Synonyms:
CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Species:
Human SOCS1 (8651), Mouse Socs1 (12703), Rat Socs1 (252971), chicken SOCS1 (416630), dog SOCS1 (490006), cow SOCS1 (518795), sheep SOCS1 (101107324), domestic guinea pig Socs1 (100728652), naked mole-rat Socs1 (101729320)
UniProtKB ID:
Gene ID:
- Human(8651) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
- Mouse(12703) suppressor of cytokine signaling 1
- Rat(252971) suppressor of cytokine signaling 1
- chicken(416630) suppressor of cytokine signaling 1
- dog(490006) suppressor of cytokine signaling 1
- cow(518795) suppressor of cytokine signaling 1
- sheep(101107324) suppressor of cytokine signaling 1
- domestic guinea pig(100728652) suppressor of cytokine signaling 1
- naked mole-rat(101729320) suppressor of cytokine signaling 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SOCS1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-SOCS1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
PrEST Antigen SOCS1, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human