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Merck

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Synonyms:
NAT1, NET, NET1, SLC6A5
Species:
UniProtKB ID:
Gene ID:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

Product Number
Description
Species
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Species
human
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Mazindol, ≥98% (TLC), powder,
Species
rat, human
Amoxapine, ,
Species
human
Cocaine free base, ,
Species
mouse, rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Atomoxetine for impurity A identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Atomoxetine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Maprotiline hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Desipramine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
(R)-Tomoxetine hydrochloride, solid,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human