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Merck

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Synonyms:
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT
Species:
Human SERPINA1 (5265), Rat Serpina1 (24648), Zebrafish serpina1 (322701), domestic cat SERPINA1 (101080897), dog SERPINA1 (480422), chicken SERPINA1 (423434), cow SERPINA1 (280699), sheep SERPINA1 (443388)
UniProtKB ID:
P01009, A6PX14, B2RDQ8, Q0PVP5, Q13672, Q53XB8, Q5U0M1, Q7M4R2
Gene ID:
  • Human(5265) Summary: The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(24648) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • Zebrafish(322701) serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • domestic cat(101080897) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • dog(480422) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • chicken(423434) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • cow(280699) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • sheep(443388) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4200198
Anti-Alpha-1-Antitrypsin (AAT) antibody,Mouse monoclonal, clone 1C2, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot
A0409
Anti-α1-Antitrypsin antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
ELISA
immunoelectrophoresis

Proteins

Product Number
Description
Species
SRP6260
SERPINA1/A1AT human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
A9024
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human
A6150
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human