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PUM1

pumilio RNA-binding family member 1

Synonyms:
HSPUM, PUMH, PUMH1, PUML1
Species:
UniProtKB ID:
Gene ID:
  • Human(9698) Summary: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(80912) pumilio 1 (Drosophila)
  • Rat(362609) pumilio homolog 1 (Drosophila)
  • Thale Cress(817469) pumilio 1
  • chicken(419554) pumilio homolog 1 (Drosophila)
  • Zebrafish(394176) pumilio homolog 1 (Drosophila)
  • domestic cat(101093375) pumilio homolog 1 (Drosophila)
  • Horse(100070514) pumilio homolog 1 (Drosophila)
  • dog(478158) pumilio homolog 1 (Drosophila)
  • cow(535450) pumilio homolog 1 (Drosophila)
  • sheep(101120896) pumilio homolog 1 (Drosophila)
  • naked mole-rat(101698365) pumilio homolog 1 (Drosophila)
  • Domestic Rabbit(100348757) pumilio homolog 1 (Drosophila)
  • domestic guinea pig(100735839) pumilio homolog 1 (Drosophila)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PUM1 (Y1123) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-PUM1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot