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Merck

PUF60

poly-U binding splicing factor 60KDa

Synonyms:
FIR, RoBPI, SIAHBP1
Species:
Human PUF60 (22827), Mouse Puf60 (67959), Rat Puf60 (84401), chicken PUF60 (426402), dog PUF60 (607245), domestic cat PUF60 (101092241), cow PUF60 (512824), sheep PUF60 (101112401), domestic guinea pig Puf60 (100734967), naked mole-rat Puf60 (101711469)
UniProtKB ID:
Q9UHX1, A8K8K8, Q969E7, Q96D94, Q96H63, Q99628, Q9NZA0, Q9UJY7
Gene ID:
  • Human(22827) Summary: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(67959) poly-U binding splicing factor 60
  • Rat(84401) poly-U binding splicing factor 60
  • chicken(426402) poly-U binding splicing factor 60KDa
  • dog(607245) poly-U binding splicing factor 60KDa
  • domestic cat(101092241) poly-U binding splicing factor 60KDa
  • cow(512824) poly-U binding splicing factor 60KDa
  • sheep(101112401) poly-U binding splicing factor 60KDa
  • domestic guinea pig(100734967) poly-U binding splicing factor 60KDa
  • naked mole-rat(101711469) poly-U binding splicing factor 60KDa

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