PDE5A
phosphodiesterase 5A, cGMP-specific
Synonyms:
CGB-PDE, CN5A, PDE5
Species:
Human PDE5A (8654), Mouse Pde5a (242202), Rat Pde5a (171115), domestic guinea pig Pde5a (100527958), naked mole-rat Pde5a (101696421), Domestic Rabbit PDE5A (100354625), cow PDE5A (785098), cow PDE5A (281972), sheep PDE5A (100294560), sheep PDE5A (101109357) ...More
UniProtKB ID:
Gene ID:
- Human(8654) Summary: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(242202) phosphodiesterase 5A, cGMP-specific
- Rat(171115) phosphodiesterase 5A, cGMP-specific
- domestic guinea pig(100527958) phosphodiesterase 5A, cGMP-specific
- naked mole-rat(101696421) phosphodiesterase 5A, cGMP-specific
- Domestic Rabbit(100354625) phosphodiesterase 5A, cGMP-specific
- cow(785098) phosphodiesterase 5A, cGMP-specific
- cow(281972) phosphodiesterase 5A, cGMP-specific
- sheep(100294560) phosphodiesterase 5A, cGMP-specific
- sheep(101109357) phosphodiesterase 5A, cGMP-specific
- chicken(422677) phosphodiesterase 5A, cGMP-specific
- dog(403825) phosphodiesterase 5A, cGMP-specific
- Horse(100072395) phosphodiesterase 5A, cGMP-specific
- domestic cat(100533976) phosphodiesterase 5A, cGMP-specific
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDE5A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-PDE5A antibody produced in mouse, clone 1F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone, 97%,
Species
human
Sildenafil Citrate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Sildenafil for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human