PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
Synonyms:
PEPCK-C, PEPCK1, PEPCKC
Species:
Human PCK1 (5105), Mouse Pck1 (18534), Rat Pck1 (362282), Thale Cress PCK1 (829943), Zebrafish pck1 (378727), chicken PCK1 (396458), dog PCK1 (403560), domestic cat PCK1 (101089256), cow PCK1 (282855), sheep PCK1 (100037690) ...More
UniProtKB ID:
Gene ID:
- Human(5105) Summary: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]
- Mouse(18534) phosphoenolpyruvate carboxykinase 1, cytosolic
- Rat(362282) phosphoenolpyruvate carboxykinase 1 (soluble)
- Thale Cress(829943) phosphoenolpyruvate carboxykinase [ATP]
- Zebrafish(378727) phosphoenolpyruvate carboxykinase 1 (soluble)
- chicken(396458) phosphoenolpyruvate carboxykinase 1 (soluble)
- dog(403560) phosphoenolpyruvate carboxykinase 1 (soluble)
- domestic cat(101089256) phosphoenolpyruvate carboxykinase 1 (soluble)
- cow(282855) phosphoenolpyruvate carboxykinase 1 (soluble)
- sheep(100037690) phosphoenolpyruvate carboxykinase 1 (soluble)
- sheep(101117351) phosphoenolpyruvate carboxykinase 1 (soluble)
- domestic guinea pig(100724258) phosphoenolpyruvate carboxykinase 1 (soluble)
- naked mole-rat(101708730) phosphoenolpyruvate carboxykinase 1 (soluble)
- Domestic Rabbit(100355682) phosphoenolpyruvate carboxykinase 1 (soluble)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCK1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, rat
Application
western blot
Anti-PCK1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, rat
Application
western blot
Anti-PCK1 Mouse mAb (3E4), liquid, clone 3E4, Calbiochem®,
Species Reactivity
human
Application