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Merck

OPN1MW

opsin 1 (cone pigments), medium-wave-sensitive

Synonyms:
CBBM, CBD, COD5, GCP, GOP, OPN1MW1
Species:
Human OPN1MW (2652), Mouse Opn1mw (14539), Rat Opn1mw (89810), domestic guinea pig Opn1mw (100135586)
UniProtKB ID:
P04001
Gene ID:
  • Human(2652) Summary: This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
  • Mouse(14539) opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
  • Rat(89810) opsin 1 (cone pigments), medium-wave-sensitive
  • domestic guinea pig(100135586) opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)

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