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Merck

MRPL3

mitochondrial ribosomal protein L3

Synonyms:
COXPD9, MRL3, RPML3
Species:
UniProtKB ID:
Gene ID:
  • Human(11222) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq, Jul 2008]
  • Mouse(94062) mitochondrial ribosomal protein L3
  • Rat(300974) mitochondrial ribosomal protein L3
  • Zebrafish(336283) mitochondrial ribosomal protein L3
  • fruit fly(32523) mitochondrial ribosomal protein L3
  • dog(477067) mitochondrial ribosomal protein L3
  • Horse(100052750) mitochondrial ribosomal protein L3
  • cow(614906) mitochondrial ribosomal protein L3
  • domestic cat(101090962) mitochondrial ribosomal protein L3
  • chicken(420686) mitochondrial ribosomal protein L3
  • naked mole-rat(101710105) mitochondrial ribosomal protein L3
  • domestic guinea pig(100725236) mitochondrial ribosomal protein L3
  • sheep(101120882) mitochondrial ribosomal protein L3

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