MNDA
myeloid cell nuclear differentiation antigen
Synonyms:
PYHIN3
Species:
UniProtKB ID:
Gene ID:
- Human(4332) Summary: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]
- Mouse(381308) myeloid cell nuclear differentiation antigen
- Rat(304988) myeloid cell nuclear differentiation antigen
- dog(488622) myeloid cell nuclear differentiation antigen
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MNDA, (C-terminal) antibody produced in mouse, clone 1H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry